Unlockables:
Costumes
Cardboard Tube Samurai costume: Open all four special chests in Insane mode.
Murder Safari Jungle costume: Defeat Dr. Wolfington in the Cloying Odor Asylum.
Silent One Mime costume: Have a saved game from the original Penny Arcade Adventures: On The Rain-Slick Precipice Of Darkness.
Insane difficulty setting
Complete the game
Trophies:
Millionaire (Bronze): Collect one million dollars in cash.
Arsonist (Bronze): Burn down the Riverbrook Apartments.
Lab Assistant (Bronze): Complete all Bonus Missions.
Reluctant Hero (Bronze): At the beginning of the episode, refuse to join Gabe and Tycho 5 times.
The Strength To Rule (Bronze): Achieve level 30 with all party members.
Pack Rat Strikes Back (Bronze): Only use items to win a fight. No attacks or counter attacks allowed.
Moving On Up (Silver): Find the key to the Riverbrook Apartments.
Endgame (Silver): Find a ticket to the World’s Fair.
Can’t Nobody Hold You Down (Silver): Complete Episode Two.
Steel Cannibal (Silver): Fully upgrade all party member’s weapons.
POWER SURRRGE! (Gold): Max out one party member’s hit counter.
Pervert (Bronze): Inspect a pair of withered binoceros testicles with genuine enthusiasm.